MCQS Familial Breast Cancer Quiz – Test
MCQS Familial Breast Cancer Quiz – Test
Important and professionally built MCQS on Familial Breast Cancer Quiz – Test
These MCQs are designed to prepare all types of medical exams all over the world as NEET, USMLE, PLAB, BOARD EXAMS etc
Results
#1. What percentage of breast cancer cases in the UK is attributed to inherited genetic changes? ? Less than 5% of all breast cancer cases in the UK are due to inherited genetic changes
5%
Less than 5% of all breast cancer cases in the UK are due to inherited genetic changes
#2. What is the range of breast cancer risk for women with unspecified familial inheritance? ? Women with unspecified familial inheritance have a risk of developing breast cancer that is 2-10 times above the baseline risk
2-10 times the baseline risk
Women with unspecified familial inheritance have a risk of developing breast cancer that is 2-10 times above the baseline risk
#3. What is the approximate gene frequency in the population for the BRCA1 gene? ? The gene frequency in the population for the BRCA1 gene is approximately 0.0006
0.0006
The gene frequency in the population for the BRCA1 gene is approximately 0.0006
#4. What is the primary risk associated with BRCA1 mutation? ? BRCA1 mutation is associated with an increased incidence of breast and ovarian cancer
Ovarian cancer
BRCA1 mutation is associated with an increased incidence of breast and ovarian cancer
#5. What is the typical lifetime risk of developing ovarian cancer in individuals with the BRCA1 gene mutation? ? Individuals with the BRCA1 gene mutation have a 50-80% lifetime risk of developing ovarian cancer
50-80%
Individuals with the BRCA1 gene mutation have a 50-80% lifetime risk of developing ovarian cancer
#6. What is the effect of taking Tamoxifen for 5 years on breast cancer risk for women with a positive family history? ? Taking Tamoxifen for 5 years appears to reduce the risk of breast cancer by 30-50% for women with a positive family history
Reduces the risk by 30-50%
Taking Tamoxifen for 5 years appears to reduce the risk of breast cancer by 30-50% for women with a positive family history
#7. What option is typically considered for individuals 'gene positive' for BRCA1 or BRCA2 who want to reduce their breast cancer risk? ? 'Gene positive' individuals often opt for prophylactic mastectomy to significantly reduce the risk of developing breast cancer
Prophylactic mastectomy
‘Gene positive’ individuals often opt for prophylactic mastectomy to significantly reduce the risk of developing breast cancer
#8. In which specific region is the BRCA2 gene located? ? The BRCA2 gene is located on chromosome 13q
Chromosome 13q
The BRCA2 gene is located on chromosome 13q
#9. Which genetic mutation is often associated with male breast cancer? ? The BRCA2 gene mutation is often associated with an increased risk of male breast cancer
BRCA2
The BRCA2 gene mutation is often associated with an increased risk of male breast cancer
#10. Which family of drugs, in addition to tamoxifen, can reduce the risk of breast cancer for women with a positive family history? ? Aromatase inhibitors (AIs), such as anastrozole, also appear to reduce the risk of breast cancer for women with a positive family history
Aromatase inhibitors (AIs)
Aromatase inhibitors (AIs), such as anastrozole, also appear to reduce the risk of breast cancer for women with a positive family history