KELOID
KELOID MCQS/ Quiz/ Test
Some important MCQS on KELOIDS as QUIZ or TEST . These MCQs on Keloids are prepared to fulfil the requirement for all types of medical exams such as NEET, USMLE, PLAB, Promatric and ALL TYPES OF BOARD exams all over the world.
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#1. A keloid differs from a hypertrophic scar in that it: ? Keloids extend beyond the original wound, whereas hypertrophic scars remain within wound borders.
Keloids extend beyond the original wound, whereas hypertrophic scars remain within wound borders.
#2. Which treatment approach for keloids has the lowest recurrence rates according to current evidence? ? Excision + radiation (5-20% recurrence) outperforms other options. Steroid injections alone have ~50% recurrence, and surgery alone has >50% recurrence.
Excision + radiation (5-20% recurrence) outperforms other options. Steroid injections alone have ~50% recurrence, and surgery alone has >50% recurrence.
#3. A 25-year-old African American female presents with a raised, painful, and pruritic scar extending beyond the original wound margins. The scar has been progressively enlarging for over a year. What is the most likely diagnosis? A. Hypertrophic scar ? Keloids are characterized by excessive collagen deposition extending beyond the original wound margins, often seen in dark-skinned individuals and females. They are painful, itchy, and grow progressively.
Keloids are characterized by excessive collagen deposition extending beyond the original wound margins, often seen in dark-skinned individuals and females. They are painful, itchy, and grow progressively.
#4. During a histopathology review of a persistent scar, which finding would most strongly suggest keloid rather than hypertrophic scar? ? Keloids show thick, haphazardly arranged Type III collagen bundles extending into normal tissue, unlike hypertrophic scars where collagen remains organized and confined.
Keloids show thick, haphazardly arranged Type III collagen bundles extending into normal tissue, unlike hypertrophic scars where collagen remains organized and confined.
#5. Which of the following collagen types is predominantly found in keloids? ? Keloids contain thick, abnormally arranged Type III collagen bundles, unlike normal scars (Type I).
Keloids contain thick, abnormally arranged Type III collagen bundles, unlike normal scars (Type I).
#6. Which of the following is NOT a common site for keloids? ? Keloids commonly occur on the sternum, earlobes, upper arm, and chest wall, but rarely on palms.
Keloids commonly occur on the sternum, earlobes, upper arm, and chest wall, but rarely on palms.
#7. What pathological feature is seen in keloids? ? Keloids show proliferating immature fibroblasts, thick collagen, and increased vascularity.
Keloids show proliferating immature fibroblasts, thick collagen, and increased vascularity.
#8. A patient with a keloid asks why it’s darker than surrounding skin. The best explanation relates to: ? Keloids appear pinkish-black due to proliferating immature blood vessels, not melanin. This distinguishes them from post-inflammatory hyperpigmentation.
Keloids appear pinkish-black due to proliferating immature blood vessels, not melanin. This distinguishes them from post-inflammatory hyperpigmentation.
#9. Which of the following syndromes is associated with keloid formation? ? Keloids may be associated with Ehlers-Danlos syndrome (connective tissue disorder) and scleroderma.
Keloids may be associated with Ehlers-Danlos syndrome (connective tissue disorder) and scleroderma.
#10. Which adjunctive therapy for keloids works by inducing hypoxia to reduce fibroblast activity? ? Silicone sheets create a hypoxic microenvironment that downregulates fibroblast collagen production through unclear mechanisms.
Silicone sheets create a hypoxic microenvironment that downregulates fibroblast collagen production through unclear mechanisms.
#11. What is the first-line therapy for keloids? ? Intralesional triamcinolone (steroid) is first-line, reducing fibroblast proliferation and collagen synthesis.
Intralesional triamcinolone (steroid) is first-line, reducing fibroblast proliferation and collagen synthesis.
#12. A keloid patient reports worsening pain. Which pathological process is most likely responsible? ? Pain stems from mechanical nerve compression by proliferating collagen. Infection and necrosis are rare in keloids; malignancy is exceedingly unlikely.
Pain stems from mechanical nerve compression by proliferating collagen. Infection and necrosis are rare in keloids; malignancy is exceedingly unlikely.